Search - Number 3 - TARGET AND NON-TARGET RADIOBIOLOGICAL REACTIONS – ITS THRESHOLD AND NON-THRESHOLD EFFECTS

TARGET AND NON-TARGET RADIOBIOLOGICAL REACTIONS – ITS THRESHOLD AND NON-THRESHOLD EFFECTS
Cover not present   TARGET AND NON-TARGET RADIOBIOLOGICAL REACTIONS – ITS THRESHOLD AND NON-THRESHOLD EFFECTS
Category: Number 3
Publication: 3
Summary

Target theory is based on three principles: hitting the sensitive volume, damaging the sensitive volume and acceleration the primary effects of ionizing radiation on the cell. Received simple formula from target theory integrates the level of damage due to irradiation dose and the numbers of the sensitive volume and target parametrically determined. This matter made target theory for long term heuristic method for new knowledge receiving in radiobiology as well as in biology. The damages under influence of radiation are dividing into reversible and nonreversible processes. Cell death, necrosis and apoptosis are reversible damages while morphological alterations of survival cells, reactions of plasmatic membrane and organelles on irradiation are reversible processes. Well known cell processes going to damage intensification and being special mechanisms of cell response on different stress factors (crossingover, shaperons synthesis and viroid presence in system), including antropogenic, were observed as accelerators of radiation damages.